Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3B3 All Species: 46.06
Human Site: T384 Identified Species: 67.56
UniProt: Q15393 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15393 NP_036558.3 1217 135577 T384 M P L E E G D T F F F Q P R P
Chimpanzee Pan troglodytes XP_511081 1283 142840 T450 M P L E E G D T F F F Q P R P
Rhesus Macaque Macaca mulatta XP_001107025 1199 133593 T366 M P L E E G D T F F F Q P R P
Dog Lupus familis XP_536791 1217 135545 T384 M P L E E G D T F F F Q P R P
Cat Felis silvestris
Mouse Mus musculus Q921M3 1217 135532 T384 M P L E E G D T F F F Q P R P
Rat Rattus norvegicus XP_001077410 1216 135436 T384 M P L E E G D T F F F Q P R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506454 1217 135474 T384 M P L E E G D T F F F Q P R P
Chicken Gallus gallus XP_001232348 1218 135585 T384 M P L E E G D T F F F Q P R P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LVE8 1217 135603 T384 M P L E E G D T F F F Q P R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728546 1227 136598 T384 M P L E E G E T F F F A P R A
Honey Bee Apis mellifera XP_623333 1217 135272 T384 M P L E E G D T F F F A P R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188711 1141 126889 R356 V A C G R G P R S S M R V L R
Poplar Tree Populus trichocarpa XP_002312063 1213 134429 F380 L M E T E E G F Q P V F F Q P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49552 1088 121161 S323 V G S S Y G D S Q L I K L N L
Baker's Yeast Sacchar. cerevisiae Q04693 1361 153766 K462 L T S K D P N K S L V F E P S
Red Bread Mold Neurospora crassa Q7RYR4 1209 134021 A399 D F P T D P T A S Y N P V Y F
Conservation
Percent
Protein Identity: 100 94.8 98.1 99.9 N.A. 99.9 99.5 N.A. 99.6 99 N.A. 93.4 N.A. 75.4 80.5 N.A. 76.1
Protein Similarity: 100 94.8 98.2 100 N.A. 100 99.5 N.A. 99.9 99.6 N.A. 97.9 N.A. 86.9 90.2 N.A. 85.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 80 93.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 86.6 93.3 N.A. 20
Percent
Protein Identity: 58.7 N.A. N.A. 23.5 23 51
Protein Similarity: 76.1 N.A. N.A. 42 41.5 69.5
P-Site Identity: 13.3 N.A. N.A. 13.3 0 0
P-Site Similarity: 26.6 N.A. N.A. 33.3 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 7 0 0 0 13 0 0 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 13 0 69 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 69 75 7 7 0 0 0 0 0 7 0 0 % E
% Phe: 0 7 0 0 0 0 0 7 69 69 69 13 7 0 7 % F
% Gly: 0 7 0 7 0 82 7 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 7 0 0 0 7 0 0 0 7 0 0 0 % K
% Leu: 13 0 69 0 0 0 0 0 0 13 0 0 7 7 7 % L
% Met: 69 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 7 0 0 7 0 % N
% Pro: 0 69 7 0 0 13 7 0 0 7 0 7 69 7 69 % P
% Gln: 0 0 0 0 0 0 0 0 13 0 0 57 0 7 0 % Q
% Arg: 0 0 0 0 7 0 0 7 0 0 0 7 0 69 7 % R
% Ser: 0 0 13 7 0 0 0 7 19 7 0 0 0 0 7 % S
% Thr: 0 7 0 13 0 0 7 69 0 0 0 0 0 0 0 % T
% Val: 13 0 0 0 0 0 0 0 0 0 13 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 7 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _